Endocrine Abstracts

Introduction: Pituitary apoplexy is a rare clinical emergency with an incidence of 2–7% in pituitary adenomas. There does not exist any evidence-based standards of optimum care for the patients. A key controversy in management is related to the functioning of acute neurosurgical intervention. The nature of clinical presentation precludes robust randomised controlled trials. Practical guidelines are derived from high-quality observational studies. On this background, we re...

Introduction: Metabolic syndrome (MetS) consists of a constellation of metabolic abnormalities which include central obesity, hyperglycemia plus insulin resistance, high triglycerides plus low high-density lipoprotein (HDL) cholesterol and hypertension. A developing collection of proof proposes that metabolic condition is related to endocrine problems including thyroid brokenness. Thyroid brokenness in metabolic condition patients might additionally add to cardiovascular illne...

Introduction: During the perioperative period, surgical operations put patients under a great deal of physical stress. The immune system produces cytokines and other immune mediators in response to this threat. Recent studies have shown that using insulin to regulate blood glucose can reduce systemic inflammation.Objective: The objective of this research was examined how postoperative intensive insulin treatment (IIT) affects the inflammatory response in...

Background: For a thorough evaluation of the pituitary gland, it is important to understand its typical structure, including the physiological differences in size and form across age groups in both males and females.Objectives: To use magnetic resonance images to examine the size, shape, and average normal volume of the normal pituitary gland at various age groups in both genders (MRI).Material and methods: 200 individuals who unde...

Background: Constitutional delay of growth and puberty (CDGP) is the commonest cause of delayed puberty in boys and differentiation of CDGP from other causes of delayed puberty can sometimes be challenging. We report a boy with delayed puberty due to a pituitary adenoma.Case: A 15-year-old boy was referred for endocrinology consultation with concerns regarding short stature and delayed puberty. There was no history or laboratory evidence suggestive of ch...

Background: We report a case of a 35-year-old male presenting with pituitary dysfunction secondary to an optochiasmal cavernoma.The gentleman was initially referred with gynaecomastia and biochemical tests consistent with secondary hypogonadism. On further questioning he also reported extremely lethargy, difficulties with weight loss and poor libido. Examination was consistent with features of hypogonadism with reduced body hair, bilateral gynaecomastia ...

Background: Tuberculosis (TB) is an important cause of mortality and morbidity globally. Only a small proportion cases of systemic TB present with lesions spreading to meninges, sella, or ventricles. Cases of intra-sellar pituitary adenoma secondary to TB have been rarely identified, often with uncertainty on medical management as opposed to more aggressive surgical therapy. We report an interesting case of pituitary adenoma presenting with pan-hypopituitarism and posterior pi...